Poultry International - November 2019 - 26

26 ❙ PoultryInternational
COULD AVIAN FLU-RESISTANT CHICKENS BE A COMMERCIAL REALITY?
resistant, and not just resilient, to the virus and to demonstrate that they can clear the infection quickly and not
carry it so it doesn't mutate in the birds or spread to nongene-edited chickens.

that we have complementary expertise that can be
brought together in this research.

Hone: Is it likely that this geneediting technique will lead to a
trade-off with other traits?

McGrew: The ownership of the Crispr technology
is currently being contested between the University
of California and MIT. We have filed a patent application for this specific application.

McGrew: This is always a possibility so the first
experiment we will perform with the genome-edited
birds will be to monitor their growth rate and behavior.

Is the end in sight for avian
influenza in the poultry industry?
www.WATTAgNet.com/articles/8943

Hone: As well as the financial
implications, eradicating bird flu also
has implications for humans. Just
how much of a problem is this?
McGrew: The 2015 avian influenza outbreak in
the U.S. led to the slaughter of 50 million poultry
and is estimated to have had an economic cost of
US$3.2 billion. It is well established that bird flu
strains can, though very rarely, become infectious to
humans. The results may be very serious with high
death rates from infection, but the flu virus does not
often spread from person to person.

Hone: How did the collaboration
between Imperial College London
and The Roslin Institute come about?
McGrew: We have collaborated with Professor
Wendy Barclay, Professor Mike Skinner and Dr
Jason Long of UCL for several years after meeting
through a separate collaboration and realizing

Hone: Who will own the rights to the
gene-editing technique?

Hone: Cobb-Vantress is contributing
to the funding of this project so will
the company have sole commercial
rights to the technology and when can
we expect to see the first avian fluresistant birds available commercially?
McGrew: Yes, Cobb-Vantress will have the first chance
to commercialize the results, but it is impossible to say
at this juncture when the first commercial birds will be
available. We expect to conclude our research within three
to five years. At this point, we will have thoroughly examined the birds for avian flu resistance and for their health
and welfare; if the findings are extremely positive the birds
will be ready for commercial production. Certainly we see
a demand from farmers and consumers.
However, there is no global framework for regulating
gene-edited animals. At the moment, Brazil, Argentina
and Australia take a fairly lenient stance on genomeedited animals, but the EU is much more restrictive,
categorizing gene editing and GMO as the same, and the
U.S. is ambiguous.
Global genetics company Genus, which has bred pigs
resistant to porcine reproductive and respiratory syndrome
(PRRS) virus, a disease that can cause reproductive
failure, reduced growth and early death for the animals,
will act as a test case for obtaining regulatory approval
in the different global markets. The company is currently
seeking regulatory approval in China and the U.S. for its
PRRS virus-resistant pigs. ■

Jenny Hone is a freelance journalist specializing in health care and pharmaceuticals.
www.WATTAgNet.com ❙ November 2019


http://www.WATTAgNet.com/articles/8943 http://www.WATTAgNet.com

Poultry International - November 2019

Table of Contents for the Digital Edition of Poultry International - November 2019

Poultry International - November 2019
Contents
Editor’s Comment
WATTAgNet.com
10 tips for proper broiler evisceration How to improve evisceration efficiency and reduce cross-contamination at the poultry processing plant.
US Hispanic market for chicken needs to be claimed
Spain’s largest cage-free egg producer urges animal welfare
ASF offers major opportunities for poultry, egg producers
Employee ventilation training key to layer farm success
Could avian flu-resistant chickens be a commercial reality?
What does science say about poultry sustainability?
How managing layer weight and nutrition impacts egg size
Key considerations to minimize processed poultry rejects
Marketplace
Advertisers’ Index
Poultry International - November 2019 - CT1
Poultry International - November 2019 - CT2
Poultry International - November 2019 - Poultry International - November 2019
Poultry International - November 2019 - Cover2
Poultry International - November 2019 - Contents
Poultry International - November 2019 - Editor’s Comment
Poultry International - November 2019 - 3
Poultry International - November 2019 - 4
Poultry International - November 2019 - WATTAgNet.com
Poultry International - November 2019 - 10 tips for proper broiler evisceration How to improve evisceration efficiency and reduce cross-contamination at the poultry processing plant.
Poultry International - November 2019 - 7
Poultry International - November 2019 - 8
Poultry International - November 2019 - 9
Poultry International - November 2019 - US Hispanic market for chicken needs to be claimed
Poultry International - November 2019 - 11
Poultry International - November 2019 - Spain’s largest cage-free egg producer urges animal welfare
Poultry International - November 2019 - 13
Poultry International - November 2019 - 14
Poultry International - November 2019 - 15
Poultry International - November 2019 - ASF offers major opportunities for poultry, egg producers
Poultry International - November 2019 - 17
Poultry International - November 2019 - 18
Poultry International - November 2019 - 19
Poultry International - November 2019 - Employee ventilation training key to layer farm success
Poultry International - November 2019 - 21
Poultry International - November 2019 - 22
Poultry International - November 2019 - 23
Poultry International - November 2019 - Could avian flu-resistant chickens be a commercial reality?
Poultry International - November 2019 - 25
Poultry International - November 2019 - 26
Poultry International - November 2019 - What does science say about poultry sustainability?
Poultry International - November 2019 - 28
Poultry International - November 2019 - 29
Poultry International - November 2019 - How managing layer weight and nutrition impacts egg size
Poultry International - November 2019 - 31
Poultry International - November 2019 - Key considerations to minimize processed poultry rejects
Poultry International - November 2019 - 33
Poultry International - November 2019 - 34
Poultry International - November 2019 - 35
Poultry International - November 2019 - Advertisers’ Index
Poultry International - November 2019 - Cover3
Poultry International - November 2019 - Cover4
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